Furosemide helps to lose 2 to 4 kilograms of weight per day. Can I lose weight with Furosemide (Lasix)? Like other diuretics, Furosemide (Lasix) has no effect on fat cells, so the process of losing weight starts only in the case of a tendency to swelling. Furosemide, commonly known as the pharmaceutical brand Lasix, is a strong diuretic medication used to decrease fluid and salt retention resulting from various health disorders 1. It reduces swelling, or edema, which can be uncomfortable and lead to further health problems. Furosemide-induced renal calcifications in low birth weight infants may lead to glomerular and tubular dysfunction in the long-term. A concentration-dependent increase in the frequency of chromosomal aberrations was observed in human lymphocytes exposed in vitro to furosemide for 24 and 72 hr. No such effect was detected in the human fibroblast cell line. ANIMAL STUDIES: Chronic administration. Just one Furosemide (Lasix) tablet after a tumultuous feast helps to avoid swelling feet and swollen face the next morning, which means you can seem slim and fresh at work. But do not think that this medicine is a panacea for losing weight. Furosemide (Lasix) is a very powerful drug that should be used as directed by a doctor. Furosemide doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight. Furosemide will make you urinate more often and you may get dehydrated easily. Follow your doctor's instructions about using potassium supplements or getting enough salt and potassium in your diet. With successful therapy, there is a connection between furosemide and weight loss. Patients will typically experience measurable weight loss upon initiation of a diuretic secondary to the loss of water weight or excess fluid. Furosemide is a powerful drug. While it works extremely efficiently to decrease excess body fluid, it is not without.